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Kathleen L McGuire Selected Research

sansalvamide A

2/2008Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines.
9/2007Identification of Sansalvamide a analog potent against pancreatic cancer cell lines.
5/2007Scaffold targeting drug-resistant colon cancers.
8/2006Synthesis of Sansalvamide A derivatives and their cytotoxicity in the MSS colon cancer cell line HT-29.
3/2006Synthesis and novel structure-activity relationships of potent sansalvamide A derivatives.

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Kathleen L McGuire Research Topics

Disease

5Neoplasms (Cancer)
01/2022 - 11/2004
5Colonic Neoplasms (Colon Cancer)
10/2010 - 03/2006
2Urinary Bladder Neoplasms (Bladder Cancer)
01/2022 - 12/2016
1Non-Muscle Invasive Bladder Neoplasms
12/2016
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1Microsatellite Instability
10/2010
1Inflammation (Inflammations)
10/2010
1Pancreatic Neoplasms (Pancreatic Cancer)
09/2007
1Emerging Communicable Diseases (Emerging Infectious Diseases)
08/2006
1T-Cell Leukemia (Leukemia, T Cell)
07/2005
1Leukemia
07/2005

Drug/Important Bio-Agent (IBA)

5sansalvamide AIBA
02/2008 - 03/2006
3Biological ProductsIBA
10/2010 - 08/2006
2Pharmaceutical PreparationsIBA
02/2008 - 05/2007
1IntegrinsIBA
01/2022
1Immune Checkpoint InhibitorsIBA
01/2022
1Biomarkers (Surrogate Marker)IBA
01/2016
1Granzymes (Granzyme)IBA
01/2016
1Proteins (Proteins, Gene)FDA Link
10/2010
1ThymidineIBA
09/2007
1VaccinesIBA
08/2006
1Interleukin-2 (IL2)IBA
07/2005
1tax Gene Products (tax Gene Product)IBA
07/2005
1Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
11/2004

Therapy/Procedure

2Therapeutics
01/2022 - 12/2016
1Immunotherapy
01/2022
1Intravesical Administration
12/2016